Name:
N-cadherin Mouse Monoclonal
 
Description:
Mouse Monoclonal Antibody to N-cadherin
Specificity:
Human, Pig, Mouse , Rat
Applications:
ELISA, IHC, WB (Recommended dilutionWB: 1:1000-1:10000; IHC: 1:20-1:200)
Immunogen:
cadherin 2, type 1, N-cadherin (neuronal) (Calculated MW:130 kDa )
Host:
Mouse
Clonality:
Monoclonal
Isotype:
IgG2a
Conjugate:
Unconjugated
Purity:
Protein A+G purification (≥95% as determined by SDS-PAGE)
Product Form:
Liquid
Formulation:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
 
Background
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity).
 
Uniprot information:
Gene Name
N-cadherin
Uniprot ID
P19022
 
Targets:
Synonyms
Cadherin 2, CD325, CDH2, CDHN, CDw325, N cadherin, NCAD, N-cadherin, Neural cadherin
 
Research Areas:
 
Please Note: N-cadherin Mouse Monoclonal is for research use only. It is not intended for diagnostic or therapeutic use.